International scientific consortia are becoming ever more central in our efforts to address global challenges such as how to respond to major health emergencies, the development of new, clean sources of energy, and how to preserve our environment. However, traditional organisational frameworks in science are often unsuitable for the highly complex projects of these consortia. Work at these consortia takes place across internationally dispersed research sites and involves diverse stakeholder groups from distinctive domains such as science, government, and industry. Accordingly, there is a pressing need for novel organisational theory and frameworks that will advance our understanding and the practice of international scientific consortia. INSCONS is an ambitious attempt to address this need through a comprehensive, interdisciplinary study of the organisational dynamics of these consortia and their interactions with broader scientific communities, various national stakeholder groups, and industry.